Synthesis of 5-Oxo and 7-Oxopyrido[2,3-d]pyrimidines |
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Authors: | Gary L. Anderson Stephen G. Richardson |
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Abstract: | The synthesis of 4-amino-2-methylthio-5-oxopyrido[2,3-d]pyrimidine 4 and its isomer, 4-amino-2-methyl-thio-7-oxopyrido[2,3-d]pyrimidine 6 is described. The regiochemistry of the reaction of 4,6-diamino-2-methyl-thiopyrimidine 9 and diethyl ethoxymethylene malonate 12 is discussed. |
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