New synthesis of 5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine |
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Authors: | Daniel Fr hel,Alain Badorc,Jean-Marie Pereillo,Jean-Pierre Maffrand |
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Affiliation: | Daniel Fréhel,Alain Badorc,Jean-Marie Pereillo,Jean-Pierre Maffrand |
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Abstract: | This paper describes two new access routes to 5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine from 2-(2-thienyl)ethylamine or its N-(2-chlorobenzyl) derivative. One of these two syntheses involves a new ring expansion from a 6,7-dihydro[3,2-c]pyridinium derivative, chloromethylated in position 4. |
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