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HELP法在中草药分析中的应用研究-冬虫夏草的化学成分测定
引用本文:龚范,彭源贵,崔卉,梁逸曾,Foo-tim Chau. HELP法在中草药分析中的应用研究-冬虫夏草的化学成分测定[J]. 高等学校化学学报, 1999, 20(2)
作者姓名:龚范  彭源贵  崔卉  梁逸曾  Foo-tim Chau
作者单位:1. 湖南大学化学化工学院,化学计量学与化学传感技术研究所
2. 湖南省中医药研究院中药研究所,长沙,410082
3. 香港理工大学不对称合成开放实验室,应用生物与化学技术系,九龙,香港
摘    要:基于直观推导式演进特征投影(HELP)法,对冬虫夏草子座和虫体分别进行了多组分同时定性定量测定.结果表明,HELP法能减少样本提取分离的步骤,降低色谱分离条件的要求,提高检测准确度.联用色谱检测与化学计量学解析法相结合将为复杂中草药分析提供一种全新手段

关 键 词:直观推导式演进特征投影法  冬虫夏草  多组分分析

HELP Applied to Traditional Chinese Medicine Analysis-Determination of Components of Cordyceps Sinensis
GONG Fan,PENG Yuan-Gui,CUI Hui,LIANG Yi-Zeng,Alexander K. M. Leung,Foo-tim Chau. HELP Applied to Traditional Chinese Medicine Analysis-Determination of Components of Cordyceps Sinensis[J]. Chemical Research In Chinese Universities, 1999, 20(2)
Authors:GONG Fan  PENG Yuan-Gui  CUI Hui  LIANG Yi-Zeng  Alexander K. M. Leung  Foo-tim Chau
Abstract:The multicomponent qualitative and quantitative analysis of Stroma and Caterpillar body of Cordyceps sinensis were carried out by Heuristic Evolving Latent Projection(HELP) method. The procedure for resolving the twoway chromatogram/spetrum data obtained from the hyphenated instruments with HELP was developed in detail. It showed that HELP method could be used to examine the purity of chromatographic peaks, resolve overlapping peaks and finally obtain the pure chromatographic profiles and spectra for all the chemical components in the studied system. The separation ability of chromatography can be greatly improved. Moreover, the accuracy of qualitative and quantitative results could also be enhanced by means of this method. HELP method could be a promising method to the simultaneous multicomponent analysis for traditional chinese medicine.
Keywords:Heuristic evolving latent projections   Cordyceps sinensis  Multicomponent analysis
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