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Asymmetric Synthesis of Polyhydroxy Pyrrolidinonyl Nucleoside Analogues from Tartaric acid
Authors:Li Ren JIN  Jian Liang YE  Yong XIE  Jiang Hong SHI  Pei Qiang HUANG  Kyeong Eun JUNG  Hong LIM
Abstract:Asymmetric synthesis of novel optically active nucleoside analogues 7 from natural tartaric acid is described. In the given nucleoside analogues an optically active polyhydroxy pyrrolidinonyl ring is in place of the tetrahydrofuran ring.
Keywords:Nucleoside  pyrrolidinone  asymmetric synthesis
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