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Brønsted acid-catalyzed C-C bond forming reaction for one step synthesis of oxazinanones |
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| Authors: | Nazim UddinJoseph S. Ulicki F. Holger FoersterlingM. Mahmun Hossain |
| Affiliation: | Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA |
| Abstract: | An efficient Brønsted acid-catalyzed synthesis of oxazinanones (2) from corresponding Boc-imines (1) in one-step has been developed. Oxazinanones are obtained via an unprecedented tandem elimination-cycloaddition reaction. The reaction is remarkably significant given its novelty, mild reaction conditions, simplicity and low cost of the catalyst system. |
| Keywords: | Brø nsted acid catalysis Boc-imines Oxazinanones Tandem elimination-cycloaddition |
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