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A microwave-assisted, propylphosphonic anhydride (T3P®) mediated one-pot Fischer indole synthesis
Authors:Matthieu DesrosesKrzysztof Wieckowski  Marc StevensLuke R Odell
Institution:Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala Biomedical Center, Uppsala University, PO Box 574, SE-751 23 Uppsala, Sweden
Abstract:A rapid, mild, and high yielding protocol for the Fischer indolization of arylhydrazines with T3P® under microwave irradiation is described. Significant features of this method include short reaction times and preparative ease.
Keywords:Fischer indole  Microwave  Propylphosphonic anhydride  Heterocycles
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