共价有机骨架材料在分离科学中的研究进展

共价有机骨架(COFs)材料是一类由有机单体通过共价键连接而成的新型多功能结晶有机聚合物,具有比表面积大、热和化学稳定性好、结构和功能可控等优点,在气体存储、药物传递、传感和催化等方面有着广泛的应用。多样的结构和丰富的官能团也使COFs在分离科学中具有巨大的应用潜力。COFs及其复合材料作为吸附剂已被用于固相萃取、磁固相萃取、固相微萃取,以及气相色谱、高效液相色谱和毛细管电色谱的新型固定相。该文综述了近3年来COFs在分离科学中的最新进展,着重介绍了COFs在水介质、食品基质、生物样本等复杂基质中样品前处理和有机分子(包括手性和异构化合物)分离等方面的研究进展,为进一步研究COFs的应用提供参考。

Progress of Covalent Organic Frameworks in Separation Science

Covalent organic frameworks(COFs) are a novel kind of crystalline organic polymer constructed with monomers via covalent bonds.COFs possess some properties such as large specific surface areas,good thermal and chemical stability,predictable control of structures and functions,etc.Based on the outstanding properties,COFs have a wide range of applications in gas storage,drug delivery,proton conduction and heterogeneous catalysis.The diverse structures and abundant functional groups also make COFs attractive in separation science including chromatography and sample pretreatment.COFs and their composites have been employed as potential sorbents for solid phase extraction,magnetic solid phase extraction and solid phase microextraction.In addition,COFs have been used as new stationary phases for gas chromatography,high performance liquid chromatography and capillary electrochromatography.The latest progress of COFs in separation science in the past 3 years has been summarized in this article,specially highlighting the key advancements of COFs in sample pretreatment such as aqueous media,food matrices,biological samples and offering a comprehensive overview in separation of organic molecules including chiral and isomeric compounds.This review also provides a reference and outlook for further exploration on the applications of COFs.