Substrate requirements of phospholipase D from Streptomyces netropsis in the transphosphatidylation synthesis of phospolipids |
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| Authors: | L. L. Birichevskaya L. A. Eroshevskaya M. A. Kisel’ A. I. Zinchenko |
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| Affiliation: | (1) Institute of Microbiology, National Academy of Sciences of Belarus, 220141 Minsk, ul. Akad. Kuprevicha, 2;(2) Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, 220141 Minsk, ul. Akad. Kuprevicha, 5/2 |
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| Abstract: | The effect of the structure of the phospholipid substrate on the yield of phosphatidyl-5′-thymidine by transphosphatidylation catalyzed by phospholipase D from Streptomyces netropsis was studied. The reaction and product yield depended on the structures of the polar and nonpolar parts, the hydrophobic-hydrophilic balance, and the degree of unsaturation of the fatty-acids in the phospholipid substrate. __________ Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 26–29, January–February, 2006. |
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| Keywords: | phospholipase D phospholipids transphosphatidylation thymidine Streptomyces netropsis |
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