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Thiophenepropyltrichlorosilane as chemical modifier on silicagel for reversed phase chromatography
Authors:Monica W. Ericsson  A. L. Colmsjö
Affiliation:(1) Department of Analytical Chemistry, University of Stockholm, 106 91 Stockholm, Sweden
Abstract:Summary Modification of silica gel with thiophene-propyl-trichlorosilane is described as well as the synthesis of the silane. The chromatographic performance and selectivity are demonstrated with various polyaromatic compounds. Thiophene-modified silica gel was found to exhibit a selectivity comparable with both ODS-and amino-phases.
Keywords:Column liquid chromatography  Reversed phase separations  Thiophene silane  Polynuclear aromatic hydrocarbons
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