Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6- dihydroxy-2,8-dioxabicyclo[3.3.0]octane |
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Authors: | Linclau Bruno Jeffery Martin J Josse Solen Tomassi Cyrille |
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Affiliation: | University of Southampton, School of Chemistry, Highfield, Southampton SO17 1BJ, U.K. bruno.linclau@soton.ac.uk |
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Abstract: | An efficient, enantioselective synthesis of a disubstituted bis-THF scaffold 5 is described, as well as an efficient differentiation of the 1,3-diol unit. [reaction: see text] |
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