Modification of biologically active amides and amines with fluorine-containing heterocycles 4. Trifluoromethyl-containing heterocyclic pyracetam derivatives |
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| Authors: | Sokolov V. B. Aksinenko A. Yu. Epishina T. A. Goreva T. V. |
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| Affiliation: | 1.Institute of Physiologically Active Compounds, Russian Academy of Sciences, 1 Severnyi proezd, 142432, Chernogolovka Moscow Region, Russian Federation
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| Abstract: | A one-pot method for the synthesis of trifluoromethyl-containing heterocyclic pyracetam derivatives has been suggested by the reaction of pyracetam, hexafluoroacetone, and 1,3-binucleophiles, viz., 3-aminocrotononitrile, 6-aminouracyls, 6-aminothiouracyl, N-benzyl-3-aminocyclohexenone, and 2-aminothiazoline. |
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