Enantioselective hydrosilylation of prochiral ketones catalyzed by chiral BINAP-copper(I) complexes |
| |
| Authors: | Jean-Thomas Issenhuth Samuel Dagorne Stéphane Bellemin-Laponnaz |
| |
| Institution: | CNRS, université de Strasbourg, institut de chimie, 1, rue Blaise-Pascal, 67000 Strasbourg, France |
| |
| Abstract: | The CuCl/NaOt-Bu/BINAP system was found to efficiently catalyze the hydrosilylation of aryl alkyl ketones with excellent enantioselectivities by using phenyl methyl silane as a stoichiometric hydride source. High enantiomeric excesses (up to 97%) and excellent yields (up to 99%) were obtained. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
