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The enolate-imine condensation using lithium dianion of 3-hydroxybutanoate and N-acylaldimines: Enhanced stereoselectivlty by added lithium chloride |
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| Authors: | Minoru Hatanaka Oee-Sook Park Ikuo Ueda |
| Affiliation: | aThe Institute of Scientific and Industrial Research, Osaka University, Mihogaoka, Ibaraki, Osaka 567, Japan |
| Abstract: | An enolate-imine condensation using the lithium dianion of 3-hydroxy-butanoate and N-acylaldimines gave the key intermediate for the preparation of (+)-thienamycin with improved stereoselection in the presence of lithium chloride. |
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