Conformations of individual quadruplex units studied in the context of extended human telomeric DNA |
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| Authors: | Singh Vijay Azarkh Mykhailo Drescher Malte Hartig Jörg S |
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| Institution: | Department of Chemistry and Konstanz Research School Chemical Biology, University of Konstanz, 78457 Konstanz, Germany. |
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| Abstract: | G-quadruplex conformations within a sequence of three quadruplex units of human telomeric DNA were studied by two-frequency pulsed electron paramagnetic resonance (EPR) spectroscopy. In contrast to some individual G-quadruplexes, within the higher-order human telomeric sequence a (3+1) hybrid structure is formed. |
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