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C离子束放射治疗肿瘤的进展
引用本文:魏世华,刘倩.C离子束放射治疗肿瘤的进展[J].原子核物理评论,2008,25(4):402-408.
作者姓名:魏世华  刘倩
作者单位:1 兰州军区兰州总医院放射治疗中心, 甘肃 兰州 730050; 2 中国医学科学院&北京协和医学院药物研究所, 北京 100050
基金项目:国家自然科学基金 , 国家高技术研究发展计划(863计划)  
摘    要:重离子(C离子)用于肿瘤放射治疗具有物理学和生物学两方面的优势, 被誉为面向21世纪最佳放疗用射线。 综合论述了世界各国重离子束治癌的发展历史, 在日本国立放射医学综合研究所(NIRS)提供的临床试验数据基础上分析了C离子束治疗的适应症以及对正常组织的放射损伤。 此外, 通过分析潜在患者人数和治疗相关硬件与软件设备, 对C离子束治癌的运用前景做了初步评估。Heavy ions (carbon ions) were considered currently as the best radiation in radiotherapy for their two superiorities in the physical and biological properties. This paper firstly put the focus on the history of development of heavy ion radiotherapy in the world, then a comprehensive analysis of the indications and radiation damages of normal tissues in clinical trails of heavy ion therapy was made based on the published data by NIRS. Moreover, the prospect of using carbon ions in radiotherapy was estimated by analyzing the potential patients’ number, its related instruments and etc.

关 键 词:肿瘤    放射治疗    C离子    重离子    高LET
收稿时间:1900-01-01

Progress in Tumor Radiotherapy with Carbon Ion Beams
WEI Shi-hua,LIU Qian.Progress in Tumor Radiotherapy with Carbon Ion Beams[J].Nuclear Physics Review,2008,25(4):402-408.
Authors:WEI Shi-hua  LIU Qian
Institution:1 Department of Radiotherapy, General Hospital of Lanzhou Military Area, Lanzhou 730050, China;2 Institute of Materia Medica & Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China)
Abstract:Heavy ions(carbon ions)were considered currently as the best radiation in radiotherapy for their two superiorities in the physical and biological properties.This paper firstly put the focus on the history of development of heavy-ion radiotherapy in the world,then a comprehensive analysis of the indications and radiation damages of normal tissues in clinical trails of heavy-ion therapy was made based on the published data by NIRS.Moreover,the prospect of using carbon ions in radiotherapy was estimated by analyzing the potential patients' number,its related instruments and etc.
Keywords:tumor  radiotherapy  carbon ion  heavy ion  high-LET
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