Bioactivities and structural studies of withanolides fromWithania somnifera |
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| Authors: | S Arshad Jamal Samina Qureshi Samina Noor Ali M Iqbal Choudhary Atta-Ur-Rahman |
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| Institution: | (1) H. E. J. Research Institute of Chemistry, University of Karachi, 75274 Karachi, Pakistan |
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| Abstract: | Four bioactive withanolides withalactone (1), withaoxylactone (2), quresimine-A (4 -hydroxy, 3-methoxy-5, 6-epoxy-(22R)-witha-24-enolide) (3) and quresindne-B (4, 27 dihydroxy-3-methoxy-5, 6-epoxy-(22R)-witha-24-enolide (4) have been isolated from the herbs of Withania somnifera, Dunal (Solanaceae). The elucidation of their structures is based on extensive spectroscopic studies, such as1H-NMR, COSY-45°, HMBC, HMQC HOHAHA, E.I., FAB (+ ve), and HR MS, etc.Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1200–1213, September, 1995. |
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