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Synthesis and properties of 2-(2-oxoindolin-3-ylidene)-2-cyanoacetic acid piperidides and morpholides
Authors:S. V. Ukhov  M. E. Konshin
Affiliation:(1) Perm Pharmaceutical Institute, 614600 Perm
Abstract:The reaction of isatins with cyanoacetic acid piperidide or morpholide gives the corresponding derivatives of 2-(2-oxoindolin-3-ylidene)-2-cyanoacetic acid, which may be reduced to give amides of 2-(2-oxoindolin-3-yl)-2-cyanoacetic acid and react with ethanolic alkali to give quinoline derivatives.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No.12, pp. 1611–1613, December 1992.
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