A Highly Selective Turn-On Fluorescent Probe for the Detection of Zinc |
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| Authors: | Ling-Yi Shen Xiao-Li Chen Xian-Jiong Yang Hong Xu Ya-Li Huang Xing Zhang Carl Redshaw Qi-Long Zhang |
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| Institution: | 1.The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550014, China;2.School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China; (X.-L.C.); (H.X.); (Y.-L.H.); (X.Z.);3.Department of Chemistry, University of Hull, Cottingham Road, Hull, Yorkshire HU6 7RX, UK; |
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| Abstract: | A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification of Zn2+. 1H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe L. An emission titration experiment in the presence of different molar fractions of Zn2+ was used to perform a Job’s plot analysis. The results showed that the stoichiometric ratio of the complex formed by L and Zn2+ was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand L coordinates with one Cu atom in the asymmetric unit. On adding CuCl2 to the ZnCl2/L system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu2+ displaced Zn2+ to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe L. |
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| Keywords: | fluorescent probe Schiff base crystal structure titration experiments |
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