FT-IR analysis of single human normal and leukemic lymphocytes

The infrared spectra of single human normal and leukemic lymphocytes have been obtained by means of the microscope-FT-IR system. Substantial differences between the two kinds of cells have been observed at level of the O-P-O vibrations of the DNA and of the proteic components. This determination opens up the possibility in determining the early stages of leukemia, in following the course of patients under therapy, and in evaluation of the residual neoplastic disease.