Synthesis of the putative structure of fistulosin using the ruthenium-catalyzed cycloisomerization of diene |
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| Authors: | Terada Yukiyoshi Arisawa Mitsuhiro Nishida Atsushi |
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| Affiliation: | Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. |
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| Abstract: | Fistulosin 1, which was isolated from the root of the Welsh onion, is a novel indole alkaloid that has antifungal activity. The first total synthesis of the reported structure of fistulosin using our cycloisomerization of diene is described. |
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