Synthesis and characterization of siloxane sulfobetaine antimicrobial agents |
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Authors: | Shiguo Chen Shaojun Chen Song Jiang Yangmiao Mo Jiaoning Tang Zaochuan Ge |
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Institution: | Shenzhen Key Laboratory of Special Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, PR China |
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Abstract: | In this paper, we report a novel antibacterial agent siloxane sulfobetaine (SSB) with reactive siloxane groups, which can be bonded onto the glass surface, rendering excellent antibacterial activity and good durability. Their antibacterial rate against Escherichia Coli and Staphylococcus aureus reach 99.96% and 99.98%, respectively, within the 24 h contact time. Their antibacterial rates of SSB coated glass surface are still beyond 95.0% after 20 washes. Moreover, SSB does not induce a skin reaction and is nontoxic to animals. Therefore, the SSB has great applications in biomaterial applications requiring durable bacteriostasis. |
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