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量子点电化学发光及其在生物分析中的应用
引用本文:席强,王捷,陈钰,刘仲明. 量子点电化学发光及其在生物分析中的应用[J]. 化学研究, 2014, 0(2): 209-216
作者姓名:席强  王捷  陈钰  刘仲明
作者单位:[1]广州军区广州总医院医学实验科,广东广州510010 [2]华南理工大学生物科学与工程学院,广东广州510006
基金项目:广东省教育厅产学研结合项目(20108090400187);广东省科技基础条件建设项目(20128060100005).
摘    要:量子点作为一种新型的电化学发光体具有独特的理化性质,是电化学发光分析领域的研究热点之一.本文简要介绍了量子点电化学发光的机理,回顾了近几年来功能化量子点作为电化学发光体在免疫分析、核酸分析、适体分析、细胞表面聚糖分析等方面的应用,并对其今后的发展方向作了展望.

关 键 词:量子点  电化学发光  机理  免疫分析  核酸分析

Electrochemiluminescence of quantum dots and their applications in bioassay
XI Qiang,' z,WANG Jie,.,CHEN Yu,LIU Zhongming. Electrochemiluminescence of quantum dots and their applications in bioassay[J]. Chemical Research, 2014, 0(2): 209-216
Authors:XI Qiang  ' z  WANG Jie  .  CHEN Yu  LIU Zhongming
Affiliation:1 (1. Department of Medical Research, General Hospital of Cruangzhou Military Command, Guangzhou 510010, Cxuangdong, China 2. School of Bioscience and Bioengineering, South China University of Technology, Cruangzhou 510006, Cruangdong, China)
Abstract:As a type of new electrochemiluminescence emitters with unique chemical and physi- cal properties, quantum dots have become a spotlight in the area of electrochemiluminescence analysis. In this paper, the basic electrochemiluminescence mechanisms of quantum dots are briefly described, and their analytical applications in immunoassay, DNA analysis, aptasensing and cytosensing are reviewed. Furthermore, the development trend of quantum dot electro- chemiluminescence is prospected.
Keywords:quantum dots electrochemiluminescence  mechanism  immunoassay  DNA analy- SIS
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