Synthesis of tritium-labeled compounds using a fibroid carbon carrier

The results of tritium labeling of organic compounds by solid phase catalysis, using fibrous carbon, were compared with those, obtained by using activated carbon purchased from Norit. It was found that utilization of multi-wall carbon nanotubes lead to a considerable growth of the yield (10–20 times) and molar radioactivity (1.5–2 times) of the labeled compounds. Using such a carrier it became possible to obtain a tritium-labeled biologically active compound like diazepam, Etomidate, and phenylalanine with molar reactivity 10–25 Ci/mmol.