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Re-emergence of the important role of radionuclide generators to provide diagnostic and therapeutic radionuclides to meet future research and clinical demands |
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| Authors: | F F Knapp Jr M R A Pillai J A Osso Jr Ashutosh Dash |
| Institution: | 1. Medical Radioisotope Program, Oak Ridge National Laboratory (ORNL), Bldg. 4501, MS 6229, 1 Bethel Valley Rd, PO Box 2008, Oak Ridge, TN, 37831-6229, USA 2. Molecular Group of Companies, Kochi, 680001, Kerala, India 3. Division of Physical and Chemical Sciences, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna International Centre, PO Box 100, 1400, Vienna, Austria 4. Isotope Production and Applications Division, Bhabha Atomic Research Centre (BARC), Trombay, Mumbai, 400 085, India |
| Abstract: | Radionuclide generators have been the main stay of diagnostic nuclear medicine and it is no exaggeration to state that the growth of nuclear medicine would not have happened to the present levels but for the availability of 99Mo/99mTc generator. This article provides a brief account of the various radionuclide generators currently in clinical use or which have made substantial progress or likely to be materialized in the foreseeable future to bring evolutional progress in nuclear medicine. Further, a brief outline on the regulatory challenges and impact on radionuclide generator technology with the emergence of professionally run central radiopharmacies have been provided. |
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