| Detection and Characterization of Non-covalent Complex between Lappaconitine and β-Cyclodextrin by Electrospray ionization Tandem Mass Spectrometry |
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| 作者姓名： | Qing Xuan XU Li LI Hao YUE Zhi Qiang LIU Ming Quart GUO Shu Ying LIU |
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| 作者单位： | Qing Xuan XU，Li LI，Hao YUE，Zhi Qiang LIU，Ming Quan GUO，Shu Ying LIU1 Laboratory of New Drug Research and Mass Spectrometry，Changchun Institute of Applied Chemistry，Chinese Academy of Sciences Changchun 130022 |
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| 基金项目： | Acknowledgment
This work was supported by the National Natural Science Foundation of China （No. 30472134, 20173057）, the State Great Basic Research Project of China （No. 2003CCA03100） and the Great Research Project of Chinese Academy of Sciences （No. KGCX2-SW-213-06）. |
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| 摘 要： | Lappaconitine(LA), exhibits antiarrhythm1 and analgesic actions2-5, and has been used to release pain for cancer patients. However, its application is limited due to poor water solubility. But its non-covalent complexes with CDs can solve this problem, th…
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| 关 键 词： | Lappaconitine β-cyclodextrin non-covalent complex ESI-MS CID. |
| 收稿时间： | 2005-05-11 |
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