Affiliation: | (1) National Institute of Standards and Technology, Gaithersburg, MD 20899-8392, USA;(2) National Institutes of Health, Office of Dietary Supplements, Bethesda, MD 20892, USA;(3) Food and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, MD 20993, USA;(4) National Research Council Canada, Ottawa, ON, K1A 0R9, Canada;(5) ChromaDex, Inc., Boulder, CO 80301, USA;(6) Eurofins, Petaluma, CA 94952, USA;(7) NSF International, Ann Arbor, MI 48105, USA;(8) Midwest Research Institute, Kansas City, MO 64110, USA;(9) Caravan Products, Totowa, NJ 07512, USA;(10) CAMAG, Muttenz, Switzerland |
Abstract: | A suite of three ginkgo-containing dietary supplement Standard Reference Materials (SRMs) has been issued by the National Institute of Standards and Technology (NIST) with certified values for flavonoid aglycones, ginkgolides, bilobalide, and selected toxic trace elements. The materials represent a range of matrices (i.e., plant, extract, and finished product) that provide different analytical challenges. The constituents have been determined by at least two independent analytical methods with measurements performed by NIST and at least one collaborating laboratory. The methods utilized different extractions, chromatographic separations, modes of detection, and approaches to quantitation. The SRMs are primarily intended for method validation and for use as control materials to support the analysis of dietary supplements and related botanical materials. Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. |