Facile palladium-catalysed synthesis of 1-aryl-1H-indazoles from 2-bromobenzaldehydes and arylhydrazines |
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Authors: | Cho Chan Sik Lim Dong Kwon Heo Nam Ho Kim Tae-Jeong Shim Sang Chul |
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Affiliation: | Research Institute of Industrial Technology, Kyungpook National University, Daegu 702-701, Korea. |
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Abstract: | 2-Bromobenzaldehydes react with arylhydrazines in toluene at 100 [degree]C in the presence of a catalytic amount of a palladium catalyst and phosphorus chelating ligands such as 1,1[prime or minute]-bis(diphenylphosphino)ferrocene and 1,3-bis(diphenylphosphino)propane along with NaO-t-Bu to afford 1-aryl-1H-indazoles in good yields. |
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