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Facile palladium-catalysed synthesis of 1-aryl-1H-indazoles from 2-bromobenzaldehydes and arylhydrazines
Authors:Cho Chan Sik  Lim Dong Kwon  Heo Nam Ho  Kim Tae-Jeong  Shim Sang Chul
Affiliation:Research Institute of Industrial Technology, Kyungpook National University, Daegu 702-701, Korea.
Abstract:2-Bromobenzaldehydes react with arylhydrazines in toluene at 100 [degree]C in the presence of a catalytic amount of a palladium catalyst and phosphorus chelating ligands such as 1,1[prime or minute]-bis(diphenylphosphino)ferrocene and 1,3-bis(diphenylphosphino)propane along with NaO-t-Bu to afford 1-aryl-1H-indazoles in good yields.
Keywords:
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