Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion |
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| Authors: | Pajewski Robert Ferdani Riccardo Schlesinger Paul H Gokel George W |
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| Affiliation: | Department of Molecular Biology & Pharmacology, Washington University School of Medicine, Campus Box 8103, 660 S. Euclid Ave., St. Louis, MO 63110, USA. |
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| Abstract: | The channel-forming diglycolylated heptapeptides containing the amino acid sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly have been found to complex chloride in CDCl(3). The strength of the interaction depends on the terminal alkyl groups and on chloride's countercation. |
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