Synthesis of an S-linked glycopeptide analog derived from human Tamm-Horsfall glycoprotein |
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| Authors: | Zhu Xiangming Haag Tobias Schmidt Richard R |
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| Institution: | Fachbereich Chemie, Universit?t Konstanz, Fach M 725, D-78457 Konstanz, Germany. |
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| Abstract: | Direct base catalyzed S-glycosylation of a cysteine and a homocysteine containing peptide with O-acetyl protected bromides in DMF-water solution furnished two glycopeptide fragments. The two glycopeptide fragments were linked to the target glycopeptide with two S-glycosyl residues mimicking a part of Tamm-Horsfall glycoprotein. |
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