A carbohydrate-based approach for the total synthesis of 1,3-polyol/alpha-pyrone antifungal natural products |
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Authors: | Ramana C V Srinivas Burgula Puranik Vedavati G Gurjar Mukund K |
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Affiliation: | National Chemical Laboratory, Dr. Homi Bhabha Road, Pune-411 008, India. vr.chepuri@ncl.res.in |
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Abstract: | [Chemical reaction: see text] An elimination and stereoselective hydrogenation of alpha-D-glucoheptonic-gamma-lactone derivative has been applied to prepare a differentially protected anti,anti-1,3,5-triol system, the utility of which has been extended for the total synthesis of anti-fungal 1,3-polyol/alpha-pyrone natural products. |
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