One-pot amidation of olefins through Pd-catalyzed coupling of alkylboranes and carbamoyl chlorides |
| |
| Authors: | Yasui Yoshizumi Tsuchida Sayo Miyabe Hideto Takemoto Yoshiji |
| |
| Affiliation: | Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. |
| |
| Abstract: | A one-pot synthesis of C1-elongated amides starting from olefins and carbamoyl chlorides has been developed. Alkylboranes, generated by hydroboration of terminal olefins with 9-BBN-H, underwent smooth coupling with carbamoyl chlorides in the presence of palladium catalyst and Cs2CO3. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
