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胶原蛋白-葡甘聚糖-软骨素共混膜的结构表征和物理性能研究
引用本文:王碧,张廷有,王坤余,但卫华,叶勇.胶原蛋白-葡甘聚糖-软骨素共混膜的结构表征和物理性能研究[J].化学研究与应用,2003,15(6):768-770.
作者姓名:王碧  张廷有  王坤余  但卫华  叶勇
作者单位:1. 四川大学皮革化学与工程教育部重点实验室,四川,成都,610065
2. 四川大学皮革化学与工程教育部重点实验室,四川,成都,610065;四川大学生物质工程研究所,四川,成都,610065
基金项目:国家高技术发展计划(863计划)2001AA320609。
摘    要:用溶液共混法制备了胶原蛋白-葡甘聚糖-软骨素共混膜。并进行了FPIR,XRD,SFM分析及透光率抗张强度、断裂伸长率、吸水率、透汽性、吸附性和渗透性测试。结果表明:共混膜中胶原蛋白、葡甘聚糖及软骨素之间存在着强烈的相互作用和良好的相容性,三者共混明显改善了几种材料及二元共混膜的性能。该共混膜可望用作生物医用材料。

关 键 词:胶原蛋白  葡甘聚糖  软骨素  共混膜  结构表征  物理性能  生物医学材料
文章编号:1004-1656(2003)06-0768-03
修稿时间:2003年4月18日

Structural characterization and physical properties of collagen-Konjac glucomannan-chondritin sulfate blend films
WANG Bi,ZHANG Ting-you,WANG Kun-yu.Structural characterization and physical properties of collagen-Konjac glucomannan-chondritin sulfate blend films[J].Chemical Research and Application,2003,15(6):768-770.
Authors:WANG Bi  ZHANG Ting-you  WANG Kun-yu
Institution:WANG Bi~1,ZHANG Ting-you~1,WANG Kun-yu~
Abstract:Collagen-Konjac glucomannan-chondritin sulfate blend films was prepared successfully by the solvent-casting method. Their structure and properties were characterized by FT-IR, X-ray diffraction, SEM, optical transmittance, at the same time percent water absorption, tensile strength,elongation at break, water vapor permeability, adsorbability and penetrability were measured too. The results indicated that some strong interaction, and good compatibility existed among collagen/Konjac glucomannan and chondritin sulfate in the blend films.The water absorption and mechanical properties of it were improved markedly in comparation with binary duality blend films or each component. As a poetential biomaterial, the films will have a wide application in biomedical field.
Keywords:collagen  Konjac glucomannan  chondritin sulfate  blend  structural characterization  physical properties
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