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Multifunctional Poly(2‐oxazoline) Nanoparticles for Biological Applications
Authors:Kristian Kempe  Antje Vollrath  Hendrik W Schaefer  Tobias G Poehlmann  Christoph Biskup  Richard Hoogenboom  Stephanie Hornig  Ulrich S Schubert
Abstract:New multifunctional copoly(2‐oxazoline) nanoparticles were prepared for cell studies. The polymer contains double‐bond side chains as potential reaction sites for “thio”‐click reactions as well as a fluorescein label covalently bound to the polymer backbone. Using the nanoprecipitation technique, spherical nanoparticles of 200–800 nm were obtained. Confocal laser scanning microscopy measurements revealed the cellular uptake of the nanoparticles.
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Keywords:copolymers  fluorescence microscopy  nanoparticles  nanoprecipitation  living polymerization  poly(2‐oxazoline)
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