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First Total Synthesis of (±)-Abieta-8,11,13-trien-7-ol
作者姓名:Cheng Lu ZHANG  Ping Yan BIE  Xuan Jia PENG  Yi YANG  Xin Fu PAN*
作者单位:Cheng Lu ZHANG,Ping Yan BIE,Xuan Jia PENG,Yi YANG,Xin Fu PAN* Department of Chemistry,National Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000
摘    要:(?-Abieta-8, 11, 13-trien-7-ol (7)1was a diterpene isolated from the leaves of J. chinensis kaizuka2. To our knowledge, no total synthetic work has been reported on it. Many of this type diterpenes exhibit significant bioactivities, such as antibacterial activity3, antitumor4~5, and anti HIV6. In order to study the further relationship between the structure and bioactivities, we synthesized the title compound. To contrast with our prior work7~10, the synthesis in this work had some diffe…

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