Study of the interaction between daunorubicin and human serum albumin,and the determination of daunorubicin in blood serum samples |
| |
Authors: | Jiang Chong-Qiu Gao Ming-Xia Meng Xian-Zhe |
| |
Institution: | Department of Chemistry, Shandong Normal University, 250014, Jinan, China. gao_mx77@yahoo.com.cn |
| |
Abstract: | The interactions between daunorubicin and human serum albumin (HSA) were studied using the spectrofluorimetric method. The binding constants of daunorubicin with HSA were obtained at different temperatures. The effects of various metal ions on the binding constants of daunorubicin with HSA were also studied. The optimum conditions of fluorometric determination of daunorubicin were studied and the developed method was successfully applied to the determination of daunorubicin in serum samples. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |