A feasible method for the sensitive and selective determination of vitamin B1 with CdSe quantum dots

A novel CdSe quantum dots-based technology platform was established in aqueous solution. It can perform accurate and simple determination of vitamin B1 concentration in pharmaceutical samples with satisfactory results. Under optimum conditions, this method demonstrates high sensitivity and selectivity. A linear relationship was observed between 5.00 and 40.0 μg ml^?1 with a correlation coefficient of 0.9963 for vitamin B1 determination and a detection limit of 70 ng ml^?1. The citrate-protected CdSe quantum dots showing temperature-sensitive luminescence intensity variation and spectral shift at moderate temperature.