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Syntheses of haptens and hapten-protein conjugates for insecticide propoxur and cyhalothrin |
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| Authors: | SANG GuangMing LUO ShiNeng LIN JianGuo QIU Ling CHEN ChuanQing YANG HaiLin & XIA YongMei Key Laboratory of Nuclear Medicine Ministry of Health Jiangsu Institute of Nuclear Medicine Wuxi China School of Chemical Material Engineering Jiangnan University Wuxi China The Key Laboratory of Industrial Biotechnology China |
| Affiliation: | SANG GuangMing 1,2,LUO ShiNeng 1,LIN JianGuo 1,QIU Ling 1,CHEN ChuanQing 2,YANG HaiLin 3 & XIA YongMei 2 1Key Laboratory of Nuclear Medicine,Ministry of Health,Jiangsu Institute of Nuclear Medicine,Wuxi 214063,China 2School of Chemical , Material Engineering,Jiangnan University,Wuxi 214122,China 3The Key Laboratory of Industrial Biotechnology,China |
| Abstract: | A facile procedure was described for the hapten design of the N-methylcarbamate insecticide propoxur.Two new haptens of propoxur(hapten 1a and hapten 1b) were synthesized by introducing appropriate spacers in the pesticide aromatic moiety of the analyte molecular structure.First,the propoxur reacted with nitric acid to yield the intermediate product.Then hapten 1a was prepared via the reduction of the intermediate product,and hapten 1b was formed by the acylation of hapten 1a with succinic anhydride.In addi... |
| Keywords: | hapten design insecticide synthesis artificial antigen |
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