Polydopamine‐assisted immobilization of arginine molecules to improve hemocompatibility |
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| Authors: | Jiamao Sun Tao Fu Jianmin Sun Feng Wu Yun Liu |
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| Institution: | 1. Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China;2. College of Medicine, Xi'an Jiaotong University, Xi'an, China;3. Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, China |
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| Abstract: | TiO2 film containing 20 at% Ta (TaTiO2 film) was sol‐gel coated on NiTi alloy, and polydopamine film was used to immobilize arginine molecules onto the TaTiO2 film surface to improve hemocompatibility of NiTi alloy. X‐ray photoelectron spectroscopy analysis indicated that polydopamine film was formed and then arginine was immobilized onto the surface of TaTiO2‐coated sample. Contact angle measurement showed that the polydopamine film and the arginine molecule layer decreased surface energy and interface tension of the TaTiO2‐coated NiTi sample. The hemocompatibility tests demonstrated that immobilization of arginine molecules improved anti‐thrombogenic activity and anti‐aggregating function of the TaTiO2‐coated NiTi sample. Copyright © 2016 John Wiley & Sons, Ltd. |
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| Keywords: | NiTi alloy TiO2 dopamine arginine surface energy hemocompatibility |
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