Strained azetidinium ylides: new reagents for cyclopropanation |
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| Authors: | Couty François David Olivier Larmanjat Bénédicte Marrot Jérôme |
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| Institution: | Institut Lavoisier, Université de Versailles Saint-Quentin-en-Yvelines, 45 avenue des Etats-Unis, 78035 Versailles Cedex, France. |
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| Abstract: | Azetidinium ylides showed a remarkable ability to perform the cyclopropanation of Michael acceptors. Ephedrine-derived azetidinium ylides allowed the formation of substituted cyclopropanes in good yields and at a high level of stereoselectivity. The determination of the relative stereochemistries in the produced cyclopropanes gave some insight into the reaction mechanism. |
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