Synthesis of 1-methyl-8-(pyridin-2-yl)-3,6-diazahomoadamantane and its derivatives |
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| Authors: | A I Kuznetsov G M Mazhed T M Serova |
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| Institution: | 1.Lomonosov Moscow Academy of Fine Chemical Technology,Moscow,Russia;2.Institute of Physiologically Active Substances,Russian Academy of Sciences, Chernogolovka,Moscow oblast,Russia |
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| Abstract: | Condensation of 1-(pyridin-2-yl)butan-2-one with 1,3,6,8-tetraazatricyclo4.4.1.13, 8]dodecane gave 1-methyl-8-(pyridin-2-yl)-3,6-diazahomoadamantan-9-one
as intermediate product in the synthesis of 1-methyl-8-(pyridin-2-yl)-3,6-diazahomoadamantane and its derivatives with various
functional groups at the bridging carbon atom. |
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