[1]Analysis and Testing Center, China Pharmaceutical University, Nanjing, Jiangsu 210009, China [2]Shanghai Mass Spectrometry Center, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
基金项目：
Project supported by the National Natural Science Found~ation of China （Nos. 20175034, 20475059）.
摘 要：
Collisional damping affects the relationship between ion mass and effective cyclotron frequency in Fourier transform mass spectrometry. The exact mass calibration equation（m/z=A/f＋（mneutral/m^^＋mneutral）k＋B/f（f＋（mneutral/m^^＋mneutralk））was therefore derived from the characteristic equation of system model, force=m（dv/dt）=qE-qv×B0-ξv,a frictional damping force）, in which k is amended by the shift of observed frequency of matrix ion or other known ion in external calibration. The mass obtained by the amended calibration equation is therefore immune to collisional damping and space-charge effects on mass accuracy. The relative errors of ion mass measured were all less than 2×10^-6.
关 键 词：
质量标准 傅立叶离子变换质谱 基质辅助激光解吸电离 阻尼机构
收稿时间：
2004-10-10
修稿时间：
2004-10-10
Effect of Damping Mechanisms on Mass Calibration Equation for MALDI/FTMS
Su Yue;Wang HaoYang;Guo YinLong;Xiang BingRen;An DengKui. Effect of Damping Mechanisms on Mass Calibration Equation for MALDI/FTMS[J]. Chinese Journal of Chemistry, 2005, 23(8): 1053-1059. DOI: 10.1002/cjoc.200591053
1. Analysis and Testing Center, China Pharmaceutical University, Nanjing, Jiangsu 210009, China;2. Project supported by the National Natural Science Foundation of China (Nos. 2au0175034, 20475059).
Abstract:
Collisional damping affects the relationship between ion mass and effective cyclotron frequency in Fourier transform mass spectrometry. The exact mass calibration equation
