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Effect of age on the mechanical properties and biochemical composition of human cardiac arteries
Authors:B. O. Ozola  B. A. Purinya  L. I. Slutskii
Abstract:Conclusions 1. The human left coronary arterial wall in subjects from age 15 to 28 has better deformative properties than the right artery.2. With increasing age, a worsening of mechanical properties of the walls is observed specifically for the left coronary artery in comparison with the right coronary artery.3. Quantitative biochemical analysis of the major components of the connective tissue of the human coronary arteries (fibrillar and nonfibrillar proteins and glycoproteins) also disclosed differences among the age groups and the position of the artery (left or right).4. As a result of a dispersion analysis carried out by computer, it was found that both age and position of the artery have a significant effect on the elastin content in the arterial wall and only the age of the subject has a significant effect on the contents of collagen, tyrosine, and hexuronic acids.5. Neither age nor type of artery have a significant effect on the contents of arginine, hexosamines, and hexoses in the arterial wall.Institute of Polymer Mechanics, Academy of Sciences of the Latvian SSR, Riga. Riga Scientific-Research Institute of Traumatology and Orthopedics. Translated from Mekhanika Polimerov, No. 3, pp. 502–506, May–June, 1978.
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