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Heck cross-coupling of vinyl heteroaromatic compounds with aryl and heteroaryl halides using Pd(II) complex under phosphine-free conditions
Authors:Manne Annapurna  P Vishnuvardhan ReddySurya Prakash Singh  Mannepalli Lakshmi Kantam
Institution:Inorganic and Physical Chemistry Division, CSIR – Indian Institute of Chemical Technology (CSIR – IICT), Tarnaka, Hyderabad 500007, India
Abstract:The palladium-catalyzed cross-coupling reaction of vinyl heteroaromatic compounds with aryl bromides and heteroaryl bromides is described using air and moisture stable N,N′,N″,O-tetrafunctional Pd catalyst under phosphine-free conditions. As a result a variety of trans-1,2-disubstituted vinyl heterocycles were obtained in high to good yields.
Keywords:C&ndash  C coupling  Heck reaction  Palladium  trans-2-Styrylpyridines  Vinyl heterocycles
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