Facile deprotection of dithioacetals by using a novel 1,4-benzoquinone/cat. NaI system |
| |
Authors: | Kiyofumi Inamoto Tetsuya Yamada Sei-ichi KatoShoko Kikkawa Yoshinori Kondo |
| |
Affiliation: | Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan |
| |
Abstract: | The combination of 1,4-benzoquinone and a catalytic amount of NaI was found to be effective for the deprotection of dithioacetals. The reactions proceeded efficiently under mild, near-neutral reaction conditions, producing a wide range of aryl and alkyl aldehydes and ketones generally in high yields with good functional group compatibility. The method developed therefore represents a general, facile, and highly applicable approach for deprotecting dithioacetals. |
| |
Keywords: | Desulfurization Deprotection 1,3-Dithianes Aldehydes Ketones |
本文献已被 ScienceDirect 等数据库收录! |
|