Synthesis and characterization of superparamagnetic nanoparticles coated with fluorescent gold nanoclusters |
| |
Authors: | Email author" target="_blank">Xavier?Le?GuévelEmail author Eva-Marie?Prinz Robert?Müller Rolf?Hempelmann Marc?Schneider |
| |
Institution: | 1.Pharmaceutical Nanotechnology,Saarland University,Saarbrücken,Germany;2.Department of Physical Chemistry,Saarland University,Saarbrücken,Germany;3.Institute of Photonic Technology,Jena,Germany |
| |
Abstract: | Multifunctional nanoparticles (NPs) combining the superparamagnetism of Mn−Zn ferrite and the fluorescence property of gold
nanoclusters (NCs) have been prepared by wet chemistry. Magnetic NPs synthesized by co-precipitation method were coated several
times with oppositely charged polyelectrolytes (PEs) using the layer-by-layer technique. Common techniques (Fourier transform
infrared spectroscopy, electron microscopy, zeta potential, etc.) indicated the monodispersity and the stability of the coated
NPs providing a positive charged surface. Fluorescent gold NCs bound to a standard protein bovine serum albumin were adsorbed
on the surface of the magnetic NPs. Structural investigations proved the presence of small gold clusters (~2 nm) in a shell
surrounding the magnetic nanomaterial. The stable nanocomposite kept the original fluorescence property of the metal clusters
with 211-fold increase of the red emission (λ = 690 nm) compared to the uncoated NPs. These NPs can be moved with a permanent
magnet despite a 72-wt% increase of the non-magnetic fraction due to the PE coating and the protein adsorption. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|