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New, simple method for synthesis of cystine peptides
Authors:B Kamber  W Rittel
Institution:Chemische Forschungslaboratorien des Departements Pharmazeutika der CIBA AKTIENGESELLSCHAFT, Basel
Abstract:A report is given on the conversion of S-trityl-cysteine-containing protected peptides to cystine peptides by a reaction with iodine in methanol. The new method permits the synthesis of symmetrical, open-chain unsymmetrical, and especially cyclic cystine peptides.
Keywords:
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