New, simple method for synthesis of cystine peptides |
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Authors: | B Kamber W Rittel |
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Institution: | Chemische Forschungslaboratorien des Departements Pharmazeutika der CIBA AKTIENGESELLSCHAFT, Basel |
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Abstract: | A report is given on the conversion of S-trityl-cysteine-containing protected peptides to cystine peptides by a reaction with iodine in methanol. The new method permits the synthesis of symmetrical, open-chain unsymmetrical, and especially cyclic cystine peptides. |
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