|
|||||
|
|
Synthesis and photoactivity of phenylazonaphthalene peptide nucleic acid monomers |
|
| Authors: | Jin Du Li Miao Chen Sheng Liu Hao Bo Zhang Zhi Lu Liu |
| Affiliation: | a Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China;b Graduate School of Chinese Academy of Sciences, Beijing |
| Abstract: | Phenylazonaphthalene peptide nucleic acid (PNA)monomers were successfully synthesized,and their photoisomerization was examined.The new PNA monomers showed reversible trans-cis isomerization with UVand visible light irradiation,which might be the foundation of photo-regulating the hybridization between PNA containing phenylazonaphthalene unit and DNA.Simulta- neously,the fluorescence of the new PNA monomers might make them especially useful as structural probes. |
| Keywords: | Peptide nucleic acid Phenylazonaphthalene Photoisomerization UV-vis absorption spectrometry Fluorescence spectrometry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
| 点击此处可从《中国化学快报》浏览原始摘要信息 | |
| 点击此处可从《中国化学快报》下载全文 | |