Enantioselective Michael additions of aldehydes to nitroalkenes catalyzed with ionically tagged organocatalyst |
| |
Authors: | Radovan Šebesta Attila Latika |
| |
Affiliation: | 1. Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 84215, Bratislava, Slovakia 2. Synkola, 84215, Bratislava, Slovakia
|
| |
Abstract: | Enantioselective organocatalytic Michael additions affords useful building blocks for many biologically and medicinally relevant compounds. Ionically-tagged diphenylprolinol silyl ether efficiently catalyzes several Michael additions of aldehydes to nitroalkenes in ionic liquids. The Michael additions work well in ionic liquids; yields up to 95% and enantioselectivities up to 95% ee were achieved. Furthermore, in some cases, the catalytic system was reusable. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|