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Optical Modulation of Azobenzene‐Modified Peptide for Gold Surface Binding |
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| Authors: | Dr. Joseph M. Slocik Dr. Zhifeng Kuang Prof. Marc R. Knecht Dr. Rajesh R. Naik |
| Affiliation: | 1. Soft Matter Materials Branch, Materials and Manufacturing Directorate, Air Force Research Laboratory, Dayton, OH, USA;2. Department of Chemistry, Miami University, Miami, FL, USA;3. 711th Human Performance Wing, Air Force Research Laboratory, Dayton, OH, USA |
| Abstract: | The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications. To achieve this level of control, an azobenzene‐based optical switch is added to nanoparticle‐binding peptides in order to switch peptide conformation and attenuate binding affinity to gold surfaces via binding and dissociation of peptides. |
| Keywords: | azobenzene bionanotechnology gold nanoparticles peptides phage display |