| CO2 as Both a Selective Agent and Reaction Media in Palla-dium-Catalyzed Reductive Ullmann-Type Coupling Reaction |
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| 作者姓名： | 李金恒 谢叶香 |
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| 作者单位： | KeyLaboratoryofChemicalBiology＆TraditionalChineseMedicineResearch,CollegeofChemistryandChemicalEngineering,HunanNormalUniversity,Changsha,Hunan410081,China |
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| 基金项目： | the National Natural Science Foundation of China (No. 20202002), Hunan Province Department of Education (No. 02C211) and Hunan Normal University (2001). |
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| 摘 要： | Carbon dioxide as both a selective agent and reaction media in the palladium-catalyzed Ullmann-type coupling has been described. The results showed that aryl chlorides could be easily activated in the presence of carbon dioxide and the chemoselectivity shifted toward the palladium-catalyzed Ullmann-type coupling reaction. In liquid carbon dioxide, homocoupling reactions of aryl halides, including less reactive aryl chlorides, were carried out smoothly in moderate to good yields using Pd/C, zinc, and H2O as the catalytic system at room temperature.
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| 关 键 词： | 钯 催化剂 UIImann类型偶联反应 二氧化碳 选择性溶剂 反应媒介 芳基卤化物 |
CO_2 as Both a Selective Agent and Reaction Media in Palla-dium-Catalyzed Reductive Ullmann-Type Coupling Reaction |
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| LI,Jin-Heng XIE,Ye-Xiang Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research,College of Chemistry and Chemical Engineering,Hunan Normal University,Changsha,Hunan ,China.CO2 as Both a Selective Agent and Reaction Media in Palla-dium-Catalyzed Reductive Ullmann-Type Coupling Reaction[J].Chinese Journal of Chemistry,2004,22(9):966-970. |
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| Authors: | LI Jin-Heng XIE Ye-Xiang Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research College of Chemistry and Chemical Engineering Hunan Normal University Changsha Hunan China |
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| Institution: | LI,Jin-Heng XIE,Ye-Xiang Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research,College of Chemistry and Chemical Engineering,Hunan Normal University,Changsha,Hunan 410081,China |
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| Abstract: | Carbon dioxide as both a selective agent and reaction media in the palladium-catalyzed Ullmann-type coupling has been described. The results showed that aryl chlorides could be easily activated in the presence of carbon diox-ide and the chemoselectivity shifted toward the palladium-catalyzed Ullmann-type coupling reaction. In liquid car-bon dioxide, homocoupling reactions of aryl halides, including less reactive aryl chlorides, were carried out smoothly in moderate to good yields using Pd/C, zinc, and H2O as the catalytic system at room temperature. |
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| Keywords: | carbon dioxide a selective agent reaction media palladium Ullmann-type coupling reaction aryl halide |
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